Ganglion treats the villain's side like a real job. Kenji clocks in, deals with his incompetent boss, watches his elaborate plans get destroyed by the same hero every single time, and clocks out. The show's comedy lives in that gap between world-ending ambition and Monday morning exhaustion. By the time HOPEMAN inevitably wins again, you're not rooting for the scheme to work, you're rooting for Kenji to finally get a day off.
Kenji Isobe works as a combatant for the Ganglion Corporation, an evil company bent on world domination. The setting is Tokyo in the early 2000s. His workplace is a battlefield: he heads into schemes like the Tokyo Cedar Pollen Operation and a plan to blow up Mount Fuji wearing only a bodysuit, and the hero Hopeman beats him every time. Between those defeats he puts up with unreasonable bosses and office drama at the dawn of the compliance era. The result is a short-format action comedy about the salaryman life of a villain's foot soldier, dedicated to everyone who works for a living.