The opening disorients you on purpose. That disorientation is the whole point, you're living Gintoki's confusion before the movie pulls you into a future where the Yorozuya has shattered, where the three of them are broken in ways that matter, where the comedy still lands but it costs something now. This movie proves Gintama's real magic was never the jokes or the fights. It was always these three people choosing each other, over and over, in a world designed to keep them apart. By the end, you understand why fans waited years for this.
Gintoki's encounter with a movie pirate at a theater screening sends him tumbling five years into a nightmarish future. The pirate turns out to be an android time machine, and Edo now lies in ruins, ravaged by a deadly epidemic known as the White Plague. Shinpachi and Kagura have fallen out and hardened into lone vigilantes, and Gintoki himself vanished years ago without a trace, leaving only a strange message in his journal. Wearing a disguise supplied by the android, Gintoki works to pull his old crew back together and look into the White Plague, and he soon learns that the key to saving this future is buried in his own dark past. The film mixes absurd comedy with action and science fiction as the Yorozuya, backed by friends and allies, face a powerful enemy.