Black Jack doesn't ask for permission to save your life, and he won't apologize for the price. Each episode is a closed moral wound: a patient arrives, the system has already failed them, and this man with no license and no mercy is the only surgeon willing to operate. Pinoko watches from the sidelines, real proof that his hands have done things medicine says are impossible. The medical establishment hates him because he proves their rules were never about saving people, just protecting themselves.

Black Jack operates on the edges of global medicine, a surgeon whose hands perform the impossible while his methods defy every convention. Unlicensed and uncompromising, he travels the world taking on operations few others could attempt. His enormous fees and refusal to follow any rules make him hated by the medical establishment, even as everyone acknowledges his skill. Pinoko, a child he built from a teratoma, is his only companion and insists she is his wife. Across four episodes, the drama returns once more to Osamu Tezuka's enduring questions about the nature of life.