This show doesn't explain itself, doesn't care if you follow it, and somehow that's exactly why it works. Every joke is a non-sequitur layered on top of another non-sequitur, animation that contorts faces into shapes that shouldn't exist, dialogue that pivots mid-sentence into complete unrelated madness. The relentless pace means you never get time to question whether any of this makes sense, so you just laugh at the next absurd thing before you finish processing the last one.
In a futuristic world, the militant Maruhage Empire seizes people's hair, and with it their freedom, to make its emperor stronger. Bo-bobo, a man sporting a golden afro and steel-hard nose hairs, can hear the voices of hair and turns his own into a weapon. After he saves a teenager named Beauty from the empire's foot soldiers, the two set out to bring down Emperor Tsuru Tsurulina IV. Along the road Bo-bobo gathers new companions and clashes with a steady stream of strange villains, all in the name of protecting the world's hair. Blending adventure, comedy and science fiction, the show keeps its tone light and its humor wacky from start to finish.