The first half is a trap that looks like a cozy fantasy slice-of-life, then the second half shatters everything you built comfort in. The show's real brilliance isn't in fooling you, it's in making you care deeply about people before it demands that caring cost something. By the time the tonal whiplash hits, you're too invested to look away, and the visual direction and soundtrack become weapons that hit harder because you weren't braced for impact.
A man wakes up on a vast, snowy plain with no memory of his name or how he got there. Moments later, a huge insect-like creature bears down on him, and he flees until he is cornered. A girl named Kuon, who has animal ears and a tail, rescues him. She leads him to her town, guarding them both from giant centipede-like boro-gigiri and a strange red slime, and gives him the name Haku after a notable historical figure from the region. Haku soon learns he is the only person around without ears and a tail like hers. The pair travel to the capital of Yamato, Kuon's homeland, making friends along the way and being drawn, without realizing it, into the country's politics and internal strife. Haku works to unravel the mystery of the red slimes and to keep war from breaking out among neighboring nations.