A guy wakes up as a girl and has to fight other magical girls while his lesbian best friend suddenly wants him. The show knows exactly what it is, pure chaos wrapped in beautiful animation and voice acting that makes every line land harder than the premise has any right to. No plot arrives to ruin the joke; it's 12 episodes of "what fresh hell is this" comedic timing, and that's the entire point.

Natsuru wakes up as a girl. Not gradually. Not metaphorically. He's simply a woman now, and a talking stuffed tiger shows up to explain that he's a Kampfer: a magical fighter who must battle other Kampfers in female form, using guns, swords or magic. Along with the transformation come great strength, fighting skill and magical power, and since only girls can be Kampfers, he has to change again and again just to survive. The situation spirals quickly. His best childhood friend, a girl, develops a crush on his new female body. His school separates boys and girls into different sections, so he ends up enrolled in both. Rumors spread that he's dating himself. Meanwhile, other Kampfers attend the same school, and Natsuru can't tell which ones want a date and which ones want him gone for good. Between managing his double life, defending himself in combat and fielding romantic attention from several directions, Natsuru's ordinary high school life becomes anything but.