A girl allergy so severe it causes full-body hives is the perfect premise for a 90s romcom, and DNA² never wastes the bit. The show commits entirely to ridiculous scenarios where Junta's transformation into a world-class playboy creates cascading romantic chaos, each episode funnier than the last because the joke is structural, not punchline-dependent. The animation holds up, the comedy timing lands, and then halfway through it abruptly pivots into Dragon Ball Z territory and loses what made it special, but those first six episodes are pure, unforced hilarity that rewarded anyone paying attention to this one when it aired.

Junta Momonari has an unusual problem: being around girls triggers a severe allergic reaction. Karin, a DNA operator from the future, arrives to stop him from becoming the Mega-Playboy, a man destined to father 100 children and cause world overpopulation. When she fires the wrong DNA-altering bullet, Junta begins turning into that irresistible playboy at random moments, and the prettiest girls at school fall for him. Karin races to undo the damage before the change becomes permanent, while romantic mishaps pile up in this sci-fi comedy.