A high school girl gets possessed by Oda Nobunaga's soul mid-rescue attempt and suddenly she's holding a gun that rewrites physics. The show never bothers explaining the rules, it just keeps throwing bigger historical spirits and weirder weapon synergy at the problem until you stop asking why and start laughing at how absurd it gets. Shio doesn't want this power, doesn't understand it, and treats each fight like an inconvenient disaster that keeps interrupting her life, which is exactly the energy that makes 13 episodes of genre chaos feel earned instead of exhausting.

Shio Ogura seems like an ordinary Japanese high school student until monsters suddenly attack during her class trip to Taiwan. Agents called E-Gene Holders arrive from the government agency DOGOO, carrying weapons that hold the spirits of historical figures. When Shio tries to save a friend, the soul of Oda Nobunaga awakens within her, and she turns out to be an E-Gene Holder herself. The sci-fi action is mixed with comedy.